![]() The response is not measured at different times after treating the biological system with a single drug concentration. In other words, the response is measured after treating the biological system with different concentrations of the drug. It must be noted that these measured responses are end-point measurements. The outcome is a sigmoidal curve (dose-response curve) with bottom and top plateaus (see below). This analysis consists of plotting X values that represent the drug concentrations or function of concentrations (log concentration) vs. ![]() For example, a dose-response experiment studies how well a drug decreases the growth of tumors grown in cell culture. In pharmacology, a dose-response experiment determines the effects of a drug on cells grown in vitro. Learn more about dose-response curves with Prism curve-fitting guides. ![]() Here, we discuss the response and dose values, how to apply a non-linear regression model and evaluate your results. ![]() response and applying a non-linear regression model. The analysis consists of plotting the drug dose or concentration vs. In these experiments, an organism (cell line or animal model) is exposed to a stimulus/stressor (drug) and the response (outcome) is measured. Non-linear regression analysis is used to evaluate the results of a dose-response experiment. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |